产品货号：
Z31385
中文名称：
CSNK1A1抗体
英文名称：
Anti-CSNK1A1 Antibody (Clone#3C10F7/3C10G5/PMC01/4D12B3/3C10F7C11)
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CSNK1A1 Antibody (Clone#3C10F7/3C10G5/PMC01/4D12B3/3C10F7C11) |
| 指标别名 | casein kinase 1;alpha 1;Casein kinase I isoform alpha;CK1;CKI alpha;CSNK1A1;HLCDGP1;PRO2975 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ELISA |
| 基因名称 | CSNK1A1 |
| 克隆号 | 3C10F7/3C10G5/PMC01/4D12B3/3C10F7C11 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG |
| 免疫原 | Purified recombinant fragment of Casein Kinase Ialpha expressed in E.Coli. |
| 计算分子量 | 39KD |
| 成分 | Ascitic fluid containing 0.03% sodium azide. |
| 纯化方式 | Affinity purification |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | Casein kinase I isoform alpha is an enzyme that in humans is encoded by the°CSNK1A1 gene.The°CSNK1A1 gene is mapped to chromosome 5q32 based on an alignment of the°CSNK1A1 sequence with the genomic sequence (GRCh37).It is reported that both screens identified CK1-alpha as a bifunctional regulator of NF-kappa-B.CK1-alpha dynamically associates with the CBM complex on T cell receptor engagement to participate in cytokine production and lymphocyte proliferation.However,CK1-alpha kinase activity has a contrasting role by subsequently promoting the phosphorylation and inactivation of CARMA1.CK1-alpha has thus a dual 'gating' function which first promotes and then terminates receptor-induced NF-kappa-B.ABC DLBCL cells required CK1-alpha for constitutive NF-kappa-B activity,indicating that CK1-alpha functions as a conditionally essential malignancy gene. |
| Uniprot ID | P48729 |
| 基因名全称 | Casein kinase I isoform alpha |
| 蛋白名全称 | Casein kinase I isoform alpha |
| 推荐稀释比 | WB 1:500～1:2000 IHC 1:200～1:1000 ELISA 1:10000 |
相关搜索：CSNK1A1抗体，CSNK1A1单抗